Body Temperature - Hypothermia

Lawrie Garnett, MD
Department of Anaesthesia,
Ottawa Civic Hospital and University of Ottawa



Objectives:

  1. To review the causes of body heat loss during anaesthesia.
  2. To review the complications which can occur as a result of hypothermia.
  3. To develop strategies to prevent intraoperative heat loss.

Hypothermia - defined as a core temp of < 36o C. Most common complication in PACU; 2063 cases among 13,538 surgical inpatients; min. temp 32 C; Ottawa Civic Hospital, March 1995 to Dec 1996.

Normal core temp is 37 C; maintained within +0.2C ( interthreshold range) by an efficient thermoregulatory system; sweating at upper end and vasoconstriction at lower end. Peripheral temperature of the limbs and skin is considerably less than the core; the difference maintained by vasoconstriction. Anaesthesia adversely affects system and interthreshold range increases from 0.2 to 4o C & patient cools.

Core temp decreases by .5 -1.5 C within the first 30 min. following induction and is just as common in epidural and spinal anaesthesia. Core temp decreases because anaesthetic induced vasodilation allows heat flow from the warm core (37oC ) to the periphery (31-35oC) and the skin. Continues to drop slowly for 2-3 hours and then remains stable . Further heat loss is decreased by vasoconstriction evidenced by an increase in the difference in skin temp between the forearm and finger tip ( maximal constriction at a temp diff of 4oC).

Heat is lost by radiation, convection, conduction and evaporation. Radiation and convection are the most important but evaporation plays a major role when body cavities are exposed. Heat is gained by nonshivering thermogenesis in infants( brown fat and skeletal muscle) 2o norepi release from adrenergic nerve terminals.

Complications of Hypothermia:

1) MYOCARDIAL ISCHEMIA: lower extremity vascular surgery; 36% pts <35oC developed myocardial ischemia vs 13% >35oC, angina 18% vs 1.5%; epi = gen 1. ? 2o increased norepi.

2) HYPOXEMIA: PaO2 < 80 mmHg, 52% of hypothermia group vs 30% of normothermic group 1

3) CATECHOLAMINES: increased norepinephrine secondary to hypothermia 2 , no differences in epinephrine or cortisol levels, more hypertension in cold group

4) SHIVERING: increases VO2 reportedly up to 3-400%; 111 patients > 60 yrs, Vo2 increased by only 38%. May be due to lower metabolic rate, age , opioids. Men shiver more than women and have a higher VO2. Can be reduced by applying heat to skin surface.8

5) MORTALITY : Trauma patients, core temp < 32o C, mortality 100%, <34oC =40%, <33oC =69% 4

6) PROLONGED DRUG ACTION: Vecuronium duration of action more than doubled @ 34.5oC5.

7) COAGULATION: platelet function decreased6

8) WOUND INFECTION: 3X increased incidence of wound infection in hypothermia, prolonged hospital stay7

8) COSTS: Prolonged stay in PACU; increased nursing costs; traditional methods of warm flannels are expensive; approx. $2.50 per blanket.

Prevention of Intraoperative Heat Loss:

a) warm room

b) warm fluids

c) warm gases

d) cover patient

e) water mattress

f) forced air blanket

 

References:

  1. Frank SM et al. Anesthesiology 78: 1993
  2. Frank SM et al. Anesthesiology 82: 1995
  3. Frank SM et al. Anesthesiology 83: 1995
  4. Jurkovich GJ et al. The Journal of Trauma 27: 1987
  5. Heier T et al. Anesthesiology 74: 1991
  6. Valeri CR et al. J Thoracic Cardiovasc Surg 104: 1992
  7. Kurz A et al. NEJM 334: 19968
  8. Sharkey A et al. BJA 70: 1993